The Advanced Desktop Printer That Delivers the Features, Flexibility, Reliability and Security You Need Be free from picking and choosing between reliability, functionality and security. With Zebra's ZD400 Series 4-inch and 2-inch printers, you're assured of quality performance for years of operation, key features that keep your business moving forward and unmatched security to prevent downtime and costly cyberattacks. And, with our exclusive Zebra DNA for Printers software suite, these printers are easy to setup, operate, manage and maintain – onsite or remotely. The Zebra ZD421-HC 4-inch Desktop Printer is an ideal choice for healthcare environments that demand reliable, secure, and easy-to-use printing solutions. With its advanced features, cleanable design, and flexibility, the ZD421-HC is built to support a variety of healthcare workflows, ensuring safe and efficient operations for years to come. Whether you need patient wristbands, labels, or clinical tracking, this printer is a great solution to meet the challenges of modern healthcare. Read more
The Zebra ZD421-HC 4-inch Desktop Printer is designed specifically for the healthcare industry, delivering advanced performance and reliability to support critical workflows while ensuring patient data protection and operational efficiency.
Advanced Healthcare Design:
Intuitive and Powerful Operation:
Flexibility and Compatibility:
Easy Setup and Maintenance:
Security and Integration:
Long-Term Durability:
Healthcare Features
• Healthcare preferred white color scheme |
Standard Features
• Print methods: Thermal Transfer or Direct Thermal • ZPL and EPL programming languages • 5 status icon, 3 button user interface • USB 2.0, USB Host • Printer setup mobile app for Android and iOS via BLE (Bluetooth Low Energy 5) connection* * BLE is intended for use with Zebra printer setup mobile app only • Real Time Clock (RTC) • OpenACCESS™ for easy media loading • Dual-wall frame construction • ENERGY STAR® certified • ZebraDesigner Essentials – easy label design tool free at www.zebra.com/zebradesigner |
Physical Characteristics
Dimensions | Direct Thermal: 8.69 in. L x 6.98 in. W x 5.93 in. H 220.8 mm L x 177.5 mm W x 150.7 mm H Thermal Transfer Roll: 10.5 in. L x 8.0 in. W x 7.44 in. H 267 mm L x 202 mm W x 189 mm H Thermal Transfer Cartridge: 10.0 in. L x 8.0 in. W x 7.0 in. H 254 mm L x 202 mm W x 177 mm H |
Weight | Direct Thermal: 2.98 lbs./1.35 kg Thermal Transfer Roll: 4.52 lbs./2.05 kg Thermal Transfer Cartridge: 5.0 lbs./2.3 kg |
Printer Specifications
Operating System | Link-OS |
Resolution | 203 dpi/8 dots per mm 300 dpi/12 dots per mm (optional) |
Memory | 512 MB Flash; 256MB SDRAM 64 MB user available non-volatile memory 8 MB user available SDRAM |
Maximum Print Width | 4.09 in./104 mm for 203 dpi 4.27 in./108 mm for 300 dpi Cartridge: 4.09 in./104 mm for 203 and 300 dpi |
Maximum Print Speed | 6 in./152 mm per second (203 dpi) 4 in./102 mm per second (300 dpi) |
Media Sensors | Full width, moveable reflective/black mark sensor; multi-position transmissive/gap sensor |
Firmware | ZPL II; EPL 2; XML; ZBI; PDF Direct |
Media, Ribbon and Cartridge Characteristics
Label Length | Minimum: 0.25 in./6.4 mm Maximum: 39.0 in./991 mm |
Media Width | Direct Thermal: 0.585 in./15 mm to 4.25 in./108 mm Thermal Transfer Roll: 0.585 in./15 mm to 4.41 in./ 112 mm Thermal Transfer Cartridge: 0.585 in./15 mm to 4.65 in./118 mm |
Media Roll Size | Maximum outer diameter: 5.00 in./127 mm Core inner diameter: 0.5 in. (12.7 mm) and 1.0 in. (25.4 mm) standard, 1.5 in. (38.1), 2.0 in., (50.8 mm) and 3.0 in. (76.2 mm) using optional adapters |
Media Thickness | 0.003 in. (0.08 mm) min.; 0.0075 in. (0.19 mm) max. |
Media Types | Roll-fed or fan-fold, die cut or continuous with or without black mark, tag stock, continuous receipt paper, and wristbands |
Ribbon Outside Diameter | 2.6 in./66 mm (300 m); 1.34 in./34 mm (74 m) |
Ribbon Standard Length | Roll: 984 ft. (300 m); 243 ft. (74 m) Cartridge: 243 ft. (74 m) |
Ribbon Ratio | 1:4 ribbon to media (300 m) 1:1 ribbon to media (74 m) |
Ribbon Width | Roll: 1.33 in./33.8 mm — 4.3 in./109.2 mm Cartridge: 4.3 in./109.2 mm |
Ribbon Core I.D. | 300 meter ribbon 1 in./25.4 mm 74 meter ribbon 0.5 in./12.7 mm |
Operating Characteristics
Operating Temp. | 40° to 105° F/4.4° to 41° C |
Storage Temp. | -40° to 140° F/-40° to 60° C |
Operating Humidity | 10% to 90% non-condensing |
Storage Humidity | 5% to 95% non-condensing |
Electrical | Auto-detectable (PFC Compliant) 100-240VAC, 50-60Hz; ENERGY STAR certified; Energy Efficiency Level VI certified; optional 2750 mAh battery; Healthcare models include IEC60601-1 certified power supply |
Options
Media Handling | Dispenser/Peeler: label peel and present with label present sensor (field installable) Cutter (field installable) |
Communications | Field installable: Ethernet 10/100, 802.11ac Wi-Fi and Bluetooth 4.1 (dual radio); Serial RS-232 auto-sensing, DB-9 Factory installed: Ethernet 10/100, 802.11ac Wi-Fi and Bluetooth 4.1 (dual radio) |
Accessories
Battery | Provides power to the printer to support a full shift of printing at maximum print speed; supports all connectivity and media handling options |
Carrying Case1 | Carrying case with shoulder strap and handles makes it easy to bring your desktop printer and battery to the point of application |
Keyboard Display Unit | Zebra Keyboard Display Unit (ZKDU) unit for stand-alone printing solutions |
Enclosed Power Supply | Attached power supply accessory for cord-free installation |
Fonts/Graphics/Symbologies
Bar Code Ratios | 2:1 and 3:1 |
1D Bar Codes | Code 11, Code 39, Code 93, Code 128, ISBT-128, UPC-A, UPC-E, EAN-8, EAN-13, UPC and EAN 2-or 5-digit extensions, Plessey, Postnet, Standard 2-of-5, Industrial 2-of-5, Interleaved 2-of-5, Logmars, MSI, Codabar and Planet Code |
2D Bar Codes | Codablock, PDF417, Code 49, DataMatrix, MaxiCode, QR Code, MicroPDF, Aztec |
Fonts and Graphics | 16 resident expandable ZPL II bitmap fonts, two resident scalable ZPL fonts, five resident expandable EPL2 fonts, native open-type font support, Unicode compliant. China units include SimSun simplified Chinese font |
Printers Supplies
For industry-leading quality, service and thermal printing expertise, choose Zebra Certified Supplies to ensure consistent, optimized performance for your Zebra printer. |
Regulatory
IEC 60950-1, IEC 62368-1, EN55022 Class B, EN55024, EN55035, EN61000-3-2, EN61000-3-3, FCC Class B, ICES-003, FCC 15.209; 15.247(d), IC RSS 247, EN 300 328, EN 301 893, EN 62311, cTUVus CE Marking, VCCI, C-Tick, S-Mark, CCC, CU, BSMI, KCC, SABS, IN-Metro, BIS, NOM |
Specifications | Descriptions |
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No Specifications |
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